Exosomes are tiny, extracellular vesicles derived from cells that carry proteins, lipids, and genetic material. In microneedling, exosomes are applied topically to enhance skin repair and rejuvenation. The microneedles create micro-injuries in the skin, promoting collagen production and allowing exosomes to penetrate more effectively. These exosomes help accelerate healing, reduce inflammation, and deliver growth factors to improve skin texture, tone, and overall appearance.